교수/연구원소개

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교수

교수정보의 상세 화면
서민덕
이름
서민덕
학력
박사
전공
약학전공(과)
정보
연구실 :
약학관 312호

연구실번호 :
3450

이메일 :
mdseo@ajou.ac.kr

연구관심분야 :
Structure of Biomolecules / Structure-Function Relationship

홈페이지 :
학력
졸업연도/학교/학위
2008.08 서울대학교 박사
졸업연도/학교/학위
2002.02 서울대학교 학사
경력 2015-present            Associate Professor
2011-2015                Assistant Professor
College of Pharmacy, Ajou University, Suwon, Korea

2009-2011        Postdoctoral research fellow 
Ontario Cancer Institute, University of Toronto, Toronto, Ontario, Canada

2008-2009        Postdoctoral Associate
Research Institute of Pharmaceutical Sciences, 
College of Pharmacy, Seoul National University, Seoul, Korea
논문 및 연구활동
연구활동(주요논문)
  • [논문] Structural and dynamic insights into the subtype-specific IP3-binding mechanism of the IP3 receptor (BIOCHEMICAL JOURNAL) - 2016.07
    서민덕, 정가영, 최혜승, 이수연, 유희섭
  • [논문] Expression, purification and structural characterization of the type 1-specific ATP binding site of IP3 receptor (IP3R1-ATPA)) (PROCESS BIOCHEMISTRY) - 2015.10
    서민덕, 손우성, 정가영, 원형식, 김하늘, 석승현
  • [논문] CaBP1, a neuronal Ca2+ sensor protein, inhibits inositol trisphosphate receptors by clamping intersubunit interactions (PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA) - 2013.05
    서민덕, Masahiro Enomoto, Ana M. Rossi, James B. Ames , Peter B. Stathopulos, Colin W. Taylor, Mitsuhiko Ikura, Congmin Li, Taufiq Rahman
  • [논문] Themes and Variations in ER/SR Calcium Release Channels: Structure and Function (PHYSIOLOGY) - 2012.12
    Mitsuhiko Ikura, Peter B. Stathopulos, Fernando J. Amador, Noboru Ishiyama, 서민덕, Masahiro Enomoto
  • [논문] Structural and functional conservation of key domains in InsP3 and ryanodine receptors (NATURE) - 2012.03
    Mitsuhiko Ikura, Saroj Velamakanni, Noboru Ishiyama, Peter B. Stathopulos, Ana M. Rossi, Colin W. Taylor, Philippa Dale, Congmin Li, James B. Ames, 서민덕, Samir A. Khan
국제학술논문지
  • [논문] Crystal structure and characterization of esterase Est25 mutants reveal improved enantioselectivity toward (S)-ketoprofen ethyl ester (APPLIED MICROBIOLOGY AND BIOTECHNOLOGY) - 2017.01
    유연우, 김진영, 홍은수, 유태현, 서민덕, 석승현
  • [논문] Two distinct mechanisms of transcriptional regulation by the redox sensor YodB (PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA) - 2016.08
    이봉진, 이상재, 이인균, 이기영, 김동균, 은현종, 제수산나, 송성현, 강사욱, 김현숙, 박성진, 서민덕, 윤혜진
  • [논문] Structural and dynamic insights into the subtype-specific IP3-binding mechanism of the IP3 receptor (BIOCHEMICAL JOURNAL) - 2016.07
    서민덕, 정가영, 최혜승, 이수연, 유희섭
  • [논문] Quercetin Directly Interacts with Vitamin D Receptor (VDR): Structural Implication of VDR Activation by Quercetin (BIOMOLECULES & THERAPEUTICS) - 2016.03
    서민덕, 최혜승, 맹한주, 정가영, 이봉진, 이기영, 최호성
  • [논문] Vitamin D Receptor-Mediated Upregulation of CYP3A4 and MDR1 by Quercetin in Caco-2 cells (PLANTA MEDICA) - 2016.01
    서민덕, 채윤지, 조관형, 지은희, 노치경, 이효종, 박요한, 맹한주, 윤인수
  • [논문] Semi-Empirical Structure Determination of Escherichia coli Hsp33 and Identification of Dynamic Regulatory Elements for the Activation Process (JOURNAL OF MOLECULAR BIOLOGY) - 2015.12
    원형식, 이유섭, 이진, 류경석, Yuno Lee, 장정화, 심대원, 김은희, 이근우, 서민덕, 정태근
  • [논문] Expression, purification and structural characterization of the type 1-specific ATP binding site of IP3 receptor (IP3R1-ATPA)) (PROCESS BIOCHEMISTRY) - 2015.10
    서민덕, 손우성, 정가영, 원형식, 김하늘, 석승현
  • [논문] Crystal structures of immunoglobulin Fc heterodimers reveal the molecular basis for heterodimer formation (MOLECULAR IMMUNOLOGY) - 2015.06
    김용성, 김예진, 석승현, 서민덕, 최혜지
  • [논문] Overexpression, purification, crystallization and preliminary X-ray crystallographic analysis of SF173 from Shigella flexneri (ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS) - 2015.01
    서민덕, 유희섭, 이유섭, 석승현, 김하늘, 안정기
  • [논문] Structural insights into endoplasmic reticulum stored calcium regulation by inositol 1,4,5-trisphosphate and ryanodine receptors (BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH) - 2014.11
    서민덕, Mitsuhiko Ikura, Peter B. Stathopulos, Masahiro Enomoto, Noboru Ishiyama
  • [논문] Structures of inactive CRP species reveal the atomic details of the allosteric transition that discriminates cyclic nucleotide second messengers (ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY) - 2014.06
    이봉진, 석승현, 임후강, 원형식, 윤혜진, 차민정, 박진영, 서민덕, 이유섭
  • [논문] CaBP1, a neuronal Ca2+ sensor protein, inhibits inositol trisphosphate receptors by clamping intersubunit interactions (PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA) - 2013.05
    서민덕, Masahiro Enomoto, Ana M. Rossi, James B. Ames , Peter B. Stathopulos, Colin W. Taylor, Mitsuhiko Ikura, Congmin Li, Taufiq Rahman
  • [논문] Themes and Variations in ER/SR Calcium Release Channels: Structure and Function (PHYSIOLOGY) - 2012.12
    Mitsuhiko Ikura, Peter B. Stathopulos, Fernando J. Amador, Noboru Ishiyama, 서민덕, Masahiro Enomoto
  • [논문] Antimicrobial peptides for therapeutic applications: a review (MOLECULES) - 2012.10
    서민덕, 이봉진, Tsogbadrakh Mishig-Ochir, 원형식, 김지훈
  • [논문] Structural and functional conservation of key domains in InsP3 and ryanodine receptors (NATURE) - 2012.03
    Mitsuhiko Ikura, Saroj Velamakanni, Noboru Ishiyama, Peter B. Stathopulos, Ana M. Rossi, Colin W. Taylor, Philippa Dale, Congmin Li, James B. Ames, 서민덕, Samir A. Khan
  • [논문] Structural Studies of Inositol 1,4,5-Trisphosphate Receptor: COUPLING LIGAND BINDING TO CHANNEL GATING (JOURNAL OF BIOLOGICAL CHEMISTRY) - 2010.11
    Mitsuhiko Ikura, Jenny Chan, Katsuhiko Mikoshiba, Noboru Ishiyama, Tapas K. Mal, Takayuki Michikawa, 서민덕, Haruka Yamazaki
  • [논문] Crystal structure of the dimerization domain of human filamin A (PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS) - 2009.04
    이봉진, 석승현, 임후강, 권애란, 김형룡, 조용철, 박동은, 서민덕, 이상재
  • [논문] Membrane binding properties of EBV gp110 C-terminal domain; evidences for structural transition in the membrane environment (VIROLOGY) - 2008.09
    이봉진, 이숙경, 서민덕, 박성진
  • [논문] Thermal denaturation of apo-cyclic AMP receptor protein and noncovalent interaction between domains (MOLECULES AND CELLS) - 2008.07
    이봉진, 원형식, 최완수, 서민덕, 고현석
  • [논문] Backbone 1H, 15N, and 13C resonance assignment and secondary structure prediction of HP0495 from Helicobacter pylori (BMB REPORTS) - 2007.09
    이봉진, 박성진, 석승현, 서민덕, 김현정
  • [논문] Solution Structure of hypothetical protein, HP0495 (Y495_HELPY) from Helicobacter pylori (PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS) - 2007.06
    이봉진, 김현정, 서민덕, 박성진
  • [논문] Identification of the WW domain-interaction sites in the unstructured N-terminal domain of EBV LMP 2A (FEBS LETTERS) - 2007.01
    이봉진, 김현정, 서민덕, 박성진
국내학술논문지
  • [논문] A simple guide to the structural study on membrane proteins in detergents using solution NMR (Journal of the Korean Magnetic Resonance Society) - 2015.12
    서민덕, 심대원, 김지훈, 원형식, 이유섭
  • [논문] Oxidation-induced conformational change of Hsp33, monitored by NMR (Journal of the Korean Magnetic Resonance Society) - 2015.12
    서민덕, 이유섭, 원형식, 류경석, 김은희, 김지훈
  • [논문] Backbone NMR Assignments of an Uncharacterized Protein, SF1002 from Shigella flexneri 5a M90T (Journal of the Korean Magnetic Resonance Society) - 2015.06
    서민덕, 원형식, 정일, 정가영, 이유섭, 윤원수
  • [논문] Structural study of the C-terminus of Vanilloid Receptor 1 (Journal of the Korean Magnetic Resonance Society) - 2007.12
    이봉진, 오우택, 서민덕, 원형식
국제학술발표
  • [학술회의] Structural insights into the subtype-specific IP3-binding mechanism of the IP3 receptor (Japan-Korea Bilateral Symposium on Multi-Scale Structural Biology) - 2016.12
    서민덕
  • [학술회의] Structures of IP3 receptor to understand the regulatory mechanism (China-Korea's pharmacy in scientific & research innovation sympoium) - 2016.11
    서민덕
  • [학술회의] STRUCTURAL AND BIOPHYSICAL STUDIES OF IP3 RECEPTOR (IP3R) TO UNDERSTAND THE REGULATORY MECHANISM (52nd Japanese Peptide Symposium) - 2015.11
    서민덕
  • [학술회의] Structure of IP3 receptor: Toward understanding the regulatory mechanism (The 11th Japan-Korea Bilateral Symposium on Biological NMR & International NMR Symposium on Pharmaceutical NMR) - 2014.12
    서민덕
  • [학술회의] Structural insights into the regulatory mechanism of inositol 1,4,5-trisphosphate receptor (IP3R) (The 12th KIAS Conference on Protein Structure and Function) - 2012.10
    서민덕, Noboru Ishiyama, Mitsuhiko Ikura, Ana M. Rossi, Colin W. Taylor, Saroj Velamakanni, Peter B. Stathopulos
국내학술발표
  • [학술회의] IP3 Receptor: Structural Approach to Understand the Regulatory Mechanism (2016년 생명약학연구회 하계심포지움) - 2016.07
    서민덕
  • [학술회의] Structural study of inositol 1,4,5-triphosphate receptor (IP3R) by NMR (2015신약발굴 NMR Workshop) - 2015.02
    서민덕
  • [학술회의] Structural insights into the regulatory mechanism of IP3 receptor (IP3R) by IP3 and CaBP1 (한국자기공명학회 제 44회 총회 및 동계 학술발표회) - 2014.02
    서민덕
  • [학술회의] Complementary use of NMR and X-ray for research on the protein structure (2012 신약발굴 Workshop and JEOL User Meeting) - 2012.11
    서민덕
  • [학술회의] Structural Insights into the Regulatory Mechanism of inositol 1,4,5-trisphosphate receptor (IP3R) (2012 Structure Festival) - 2012.06
    서민덕, Noboru Ishiyama, Mitsuhiko Ikura, Ana M. Rossi, Colin W. Taylor, Saroj Velamakanni, Peter B. Stathopulos
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